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In die CLS Zellbank wurden weitere Zelllinien aufgenommen.

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22 Artikel in dieser Kategorie gefunden

  • HK (FDC/HK)

    Nummer: 300204

    Bestand: Sofort lieferbar
    Human Follicular dendritic reticulum cells (FDCs)

    Organism: Homo sapiens (human)
    Age: Unknown, child
    Gender: Unspecified; female, acc. to STR analysis conducted at CLS in-house
    Tissue: Tonsils
    Morphology: Fibroidal
    Cell type: Follicular Dendritic reticulum
    Growth Properties: Adherent
    Description: The cell line was established from tonsillar tissue after routine tonsillectomy of a child in 1994 by Kim et al. In coculture with activated (anti-CD40/anti-µ) human lymphocytes soluble factors are released by HK which support growth of normal and malignant lymphocytes.

  • HMy2 (LICR-LON-HMy2)

    Nummer: 302008

    Bestand: Sofort lieferbar
    Human Burkitt's lymphoma cell line HMy2 (LICR-LON-HMy2) cells

    Human-human hybridoma fusion partner cell line

    Organism: Homo sapiens (human)
    Age: 33 years
    Gender: Female
    Ethnicity: n.a.
    Tissue: Blood, hematopoietic system
    Disease: Normal
    Morphology: Round cells
    Cell type: B lymphoblastoid cell line
    Growth Properties: Suspension
    Description: This hybridoma fusion partner cell line was established in 1982 derived from the ARH-77 human plasma cell leukemia-derived line.
    Biosafety level: L2

    HLA-Data to be found on the product information sheet.
  • imWilms1

    Nummer: 300412

    Bestand: 3-5 Tage Lieferzeit
    Human cell line Wilms1

    Demnächst hier erhältlich

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age:
    Gender:
    Tissue: Wilms tumor
    Morphology:
    Growth Properties:
    Description: The imWilms1 cell line was established from a primary Wilms tumor by B. Royer-Pokora.
    WT1-mutation status: homozygous c. 149 C>A, p.S50X
    LOH: 11p11-11pter
    CTNNB1 mutation: heterozygous TCT>TTT, p.S45F

    References:
    Royer-Pokora et al. Wilms tumor cells with WT1 mutations have characteristic features of mesenchymal stem cells and express molecular markers of paraxial mesoderm. Human Molecular Genetics, 19 (No. 9): 1651-1668, 2010.
  • ImWilms10 T

    Nummer: 300419

    Bestand: 3-5 Tage Lieferzeit
    Human cell line ImWilms10 T

    Demnächst hier erhältlich

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age:
    Gender:
    Tissue: Wilms tumor
    Morphology:
    Growth Properties:
    Description: The ImWilms10 T cell line was established from a primary Wilms tumor by B. Royer-Pokora.
    WT1-mutation status: homozygous del WT1 within del11p13
    LOH: no LOH in 11p13 but UPD in 11p15
    CTNNB1 mutation: homozygous del TCT, p. ΔS45, UPD 3p

    References:
    Brandt A, Löhers K, Beier M, Leube B, de Torres C, Mora J, Arora P, Jat PS, Royer-Pokora B. Establishment of a Conditionally Immortalized Wilms Tumor Cell Line with a Homozygous WT1 Deletion within a Heterozygous 11p13 Deletion and UPD Limited to 11p15. PLoS One. 2016 May 23;11(5):e0155561. doi: 10.1371/journal.pone.0155561. eCollection 2016.
  • Wilms1

    Nummer: 300411

    Bestand: 3-5 Tage Lieferzeit
    Human cell line Wilms1

    Demnächst hier erhältlich

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age:
    Gender:
    Tissue: Wilms tumor
    Morphology:
    Growth Properties:
    Description: The Wilms1 cell line was established from a primary Wilms tumor by B. Royer-Pokora.
    WT1-mutation status: homozygous c. 149 C>A, p.S50X
    LOH: 11p11-11pter
    CTNNB1 mutation: heterozygous TCT>TTT, p.S45F

    References:
    Royer-Pokora et al. Wilms tumor cells with WT1 mutations have characteristic features of mesenchymal stem cells and express molecular markers of paraxial mesoderm. Human Molecular Genetics, 19 (No. 9): 1651-1668, 2010.
  • Wilms10M

    Nummer: 300418

    Bestand: 3-5 Tage Lieferzeit
    Human cell line Wilms10M

    Demnächst hier erhältlich

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age:
    Gender:
    Tissue: Wilms tumor
    Morphology:
    Growth Properties:
    Description: The Wilms10M cell line was established from a Wilms tumor metastasis by B. Royer-Pokora.
    WT1-mutation status: homozygous del WT1 within del11p13
    LOH: no LOH in 11p13 but UPD in 11p15
    CTNNB1 mutation: homozygous del TCT, p. ΔS45, UPD 3p

    References:
    Brandt A, Löhers K, Beier M, Leube B, de Torres C, Mora J, Arora P, Jat PS, Royer-Pokora B. Establishment of a Conditionally Immortalized Wilms Tumor Cell Line with a Homozygous WT1 Deletion within a Heterozygous 11p13 Deletion and UPD Limited to 11p15. PLoS One. 2016 May 23;11(5):e0155561. doi: 10.1371/journal.pone.0155561. eCollection 2016.
  • Wilms10T

    Nummer: 300417

    Bestand: 3-5 Tage Lieferzeit
    Human cell line Wilms10T

    Demnächst hier erhältlich

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age:
    Gender:
    Tissue: Wilms tumor
    Morphology:
    Growth Properties:
    Description: The Wilms10T cell line was established from a primary Wilms tumor by B. Royer-Pokora.
    WT1-mutation status: homozygous del WT1 within del11p13
    LOH: no LOH in 11p13 but UPD in 11p15
    CTNNB1 mutation: homozygous del TCT, p. ΔS45, UPD 3p

    References:
    Brandt A, Löhers K, Beier M, Leube B, de Torres C, Mora J, Arora P, Jat PS, Royer-Pokora B. Establishment of a Conditionally Immortalized Wilms Tumor Cell Line with a Homozygous WT1 Deletion within a Heterozygous 11p13 Deletion and UPD Limited to 11p15. PLoS One. 2016 May 23;11(5):e0155561. doi: 10.1371/journal.pone.0155561. eCollection 2016.
  • Wilms11

    Nummer: 300420

    Bestand: 3-5 Tage Lieferzeit
    Human cell line Wilms11

    Demnächst hier erhältlich

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age:
    Gender:
    Tissue: Wilms tumor
    Morphology:
    Growth Properties:
    Description: The Wilms11 cell line was established from a primary Wilms tumor by B. Royer-Pokora.
    WT1-mutation status: homozygous WT1 c.901c>T, p.R301X
    LOH: n.a.
    CTNNB1 mutation: wild type

    References:
    Royer-Pokora B. Busch MA, Tenbusch S, Schmidt M, Beier M, Woods AD, Thiele H, Mora J. Comprehensive Biology and Genetics Compendium of Wilms Tumor Cell Lines with Different WT1 Mutations. Cancers 2021, 13(1), 60; https://doi.org/10.3390/cancers13010060
  • Wilms2

    Nummer: 300413

    Bestand: 3-5 Tage Lieferzeit
    Human cell line Wilms2

    Demnächst hier erhältlich

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age:
    Gender:
    Tissue: Wilms tumor
    Morphology:
    Growth Properties:
    Description: The Wilms2 cell line was established from a primary Wilms tumor by B. Royer-Pokora.
    WT1-mutation status: homozygous c. 149 C>A, p.R362X
    LOH: 11p11-11pter
    CTNNB1 mutation: heterozygous TCT>TAT, p.S45Y

    References:
    Royer-Pokora et al. Wilms tumor cells with WT1 mutations have characteristic features of mesenchymal stem cells and express molecular markers of paraxial mesoderm. Human Molecular Genetics, 19 (No. 9): 1651-1668, 2010.
  • Wilms3

    Nummer: 300414

    Bestand: 3-5 Tage Lieferzeit
    Human cell line Wilms3

    Demnächst hier erhältlich

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age:
    Gender:
    Tissue: Wilms tumor
    Morphology:
    Growth Properties:
    Description: The Wilms3 cell line was established from a primary Wilms tumor by B. Royer-Pokora.
    WT1-mutation status: homozygous c. 1293-1294insA, p.V432fs87
    LOH: 11p11-11pter
    CTNNB1 mutation: wild type

    References:
    Royer-Pokora et al. Wilms tumor cells with WT1 mutations have characteristic features of mesenchymal stem cells and express molecular markers of paraxial mesoderm. Human Molecular Genetics, 19 (No. 9): 1651-1668, 2010.
    Busch M, Schwindt H, Brandt A, Beier M, Görldt N, Romaniuk P, Toska E, Roberts S, Royer HD, Royer-Pokora B. Classification of a frameshift/extended and a stop mutation in WT1 as gain-of-function mutations that activate cell cycle genes and promote Wilms tumour cell proliferation. Hum Mol Genet. 2014 Aug 1;23(15):3958-74. doi: 10.1093/hmg/ddu111. Epub 2014 Mar 11.
  • Wilms6

    Nummer: 300415

    Bestand: 3-5 Tage Lieferzeit
    Human cell line Wilms6

    Demnächst hier erhältlich

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age:
    Gender:
    Tissue: Wilms tumor
    Morphology:
    Growth Properties:
    Description: The Wilms6 cell line was established from a primary Wilms tumor by B. Royer-Pokora.
    WT1-mutation status: homozygous c. 1168C>T, p.R390X
    LOH: 11p11-11pter
    CTNNB1 mutation: homozygous del TCT, p. ΔS45

    References:
    Royer-Pokora B. Busch MA, Tenbusch S, Schmidt M, Beier M, Woods AD, Thiele H, Mora J. Comprehensive Biology and Genetics Compendium of Wilms Tumor Cell Lines with Different WT1 Mutations. Cancers 2021, 13(1), 60; https://doi.org/10.3390/cancers13010060
  • Wilms8

    Nummer: 300416

    Bestand: 3-5 Tage Lieferzeit
    Human cell line Wilms8

    Demnächst hier erhältlich

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age:
    Gender:
    Tissue: Wilms tumor
    Morphology:
    Growth Properties:
    Description: The Wilms8 cell line was established from a primary Wilms tumor by B. Royer-Pokora.
    WT1-mutation status: homozygous c. 1168C>T, p.R390X
    LOH: n.a.
    CTNNB1 mutation: heterozygous TCT>GCT, p.S45A

    References:
    Royer-Pokora B. Busch MA, Tenbusch S, Schmidt M, Beier M, Woods AD, Thiele H, Mora J. Comprehensive Biology and Genetics Compendium of Wilms Tumor Cell Lines with Different WT1 Mutations. Cancers 2021, 13(1), 60; https://doi.org/10.3390/cancers13010060