Burkitt-Lymphom Zelllinien



Das Burkitt-Lymphom als malignes Lymphom wird den B-Zell-Non-Hodgkin-Lypmphomen zugerechnet und ist einer der am schnellsten wachsenden humanen Tumore. Es ist in der Regel mit der Infektion von B Lymphozyten mit dem Epstein-Barr Virus (EBV) assoziiert.
Die Anwendung von Zelllinien, etabliert von Patienten mit Burkitt-Lymphom, umfasst beispielsweise
- HLA-Typisierung
- Entwicklung immunologischer/immuntherapeutischer Tools zur Krebsbehandlung, insbesondere Peptid-Bindungs Spezifikationen.
- Analyse von Oberflächenmolekülen/Rezeptoren als potentielle neue Tumorziele für immunologische Behandlungen oder Impfstoff-Entwicklung,
- Medikamenten-Screening in präklinischen Studien.

Artikelübersicht

14 Artikel in dieser Kategorie gefunden

  • Jiyoye

    Nummer: 300366

    Bestand: Sofort lieferbar
    Human B lymphocyte cell line

    Organism: Homo sapiens (human)
    Age: 7 years old
    Gender: Male
    Ethnicity: Black
    Tissue: Blood
    Disease: Burkitt's lymphoma
    Morphology: Lymphoblast-like, round cells
    Cell type: B-LCL, B lymphocyte
    Growth Properties: Suspension, proliferation in clusters
    Description: The Jiyoye cell line was established in 1967 from blood of a 7 year old male with Burkitt's lymphoma.
    Characteristics: Cells are positive for EBNA

    HLA-Daten to be found in the product information sheet.
  • BJAB

    Nummer: 302006

    Bestand: Sofort lieferbar
    Human B lymphocyte cell line BJAB

    Organism: Homo sapiens (human)
    Age: 5 years old
    Gender: Female
    Ethnicity: Black
    Tissue: Blood, hematopoietic system
    Disease: Burkitt's lymphoma
    Morphology: Round cells
    Cell type: B lymphocyte
    Growth Properties: Suspension, proliferation in clusters
    Description: The BJAB cell line was established in 1974 from blood of a 5 year old female with Burkitt's lymphoma.
    Characterisitics: Cells are negative for EBNA
    Biosafety level: 1
  • Daudi

    Nummer: 302009

    Bestand: Sofort lieferbar
    Human B lymphocyte cell line Daudi


    Organism: Homo sapiens (human)
    Age: 16 year old
    Gender: Male
    Ethnicity: Black
    Tissue: Blood
    Disease: Burkitts lymphoma
    Morphology: Round cells
    Cell type: B-LCL, B lymphocyte
    Growth Properties: Suspension
    Description: The Daudi cell line was established in 1967 from tumor biopsy.
    Characterisitics: Cells are positive for EBNA, to be handled under Biological safety level 2.


    HLA-Daten:
    Klasse I:
    HLA-A: A*01:02,*66:01:01
    HLA-B: B*58:01:01,*58:02:01
    HLA-C: C*03:02:02,*06:02:01
    HLA-E: E*01:03:02,*01:03:05
    Klasse II:
    DRB1: DRB1*13:01:01,*13:02:01
    DQA1: DQA1*01:02:01,*01:03:01
    DQB1: DQB1*06:02:01,*06:04:01
    DPB1: DPB1*02:01:02,*106:01
  • EB1

    Nummer: 300403

    Bestand: Sofort lieferbar
    Human Burkitt lymphoma cell line EB1

    Organism: Homo sapiens (human)
    Ethnicity: Black
    Age: 9 years old
    Gender: Female
    Tissue: Burkitt Lymphoma
    Morphology: Lymphoblast
    Cell type: B lymphocyte
    Growth Properties: Suspension, Cluster
    Description: The EB1 cell line was isolated by M.A. Epstein and Y.M. Barr in 1963 from biopsy fragments and cell clumps of a lymphoma. These were seeded into Insulin bottles in Eagle's basal medium with 10% human serum and fed by medium addition. The cells grew as free-floating singel individuals or doublets with a mean doubling time of about 48 hrs and were identified as altered lymphoblasts on the basis of growth and uniform morphology.



    HLA-Daten:
    Klasse I:
    HLA-A: A*29:02:01,*31:04:01
    HLA-B: B*47:03,*57:03:01
    HLA-C: C*07:01:02,*07:18:01
    HLA-E: E*01:03:01,*01:13
    Klasse II:
    DRB1: DRB1*11:02:01,*13:02:01
    DQA1: DQA1*01:02:01,*05:05:01
    DQB1: DQB1*03:01,*06:04:01
    DPB1: DPB1*13:01:01G,*30:01:01
  • EB1 growing

    Nummer: 330403

    Bestand: Sofort lieferbar
    Human Burkitt lymphoma cell line EB1

    Organism: Homo sapiens (human)
    Ethnicity: Black
    Age: 9 years old
    Gender: Female
    Tissue: Burkitt Lymphoma
    Morphology: Lymphoblast
    Cell type: B lymphocyte
    Growth Properties: Suspension, Cluster
    Description: The EB1 cell line was isolated by M.A. Epstein and Y.M. Barr in 1963 from biopsy fragments and cell clumps of a lymphoma. These were seeded into Insulin bottles in Eagle's basal medium with 10% human serum and fed by medium addition. The cells grew as free-floating singel individuals or doublets with a mean doubling time of about 48 hrs and were identified as altered lymphoblasts on the basis of growth and uniform morphology.




    HLA-Daten:
    Klasse I:
    HLA-A: A*29:02:01,*31:04:01
    HLA-B: B*47:03,*57:03:01
    HLA-C: C*07:01:02,*07:18:01
    HLA-E: E*01:03:01,*01:13
    Klasse II:
    DRB1: DRB1*11:02:01,*13:02:01
    DQA1: DQA1*01:02:01,*05:05:01
    DQB1: DQB1*03:01,*06:04:01
    DPB1: DPB1*13:01:01G,*30:01:01
  • Namalwa

    Nummer: 300439

    Bestand: Sofort lieferbar
    Biosafety level: L2

    Human Burkitt's Lymphoma cell line Namalwa

    Organism: Homo sapiens
    Tissue: Blood
    Morphology: Lymphoblast
    Growth Properties: Suspension
    Biosafety level: 2

  • P3HR1

    Nummer: 302310

    Bestand: Sofort lieferbar
    Biosafety level: L2

    Human B lymphocyte cell line P3HR1 (P3HR-1)
    This cell line is a clonally derived subline of the B-LCL cell line Jiyoye.


    Organism: Homo sapiens (human)
    Age: 7 years old
    Gender: Male
    Ethnicity: Black
    Tissue: Blood
    Disease: Burkitt's lymphoma
    Morphology: Lymphoblast-like, round cells
    Cell type: B-LCL, B lymphocyte
    Growth Properties: Suspension, proliferation in clusters
    Description: This derivative of the cell line Jiyoye contains high amounts of EBV.
    Characterisitics: Cells are positive for EBNA

    HLA-Daten to be found in the product information sheet.
  • RAJI

    Nummer: 300359

    Bestand: Sofort lieferbar
    Human B lymphocyte cell line RAJI

    Organism: Homo sapiens (human)
    Age: 11 year old
    Gender: Male
    Ethnicity: Black
    Tissue: Blood, hematopoietic system
    Disease: Burkitt's lymphoma
    Morphology: Round cells
    Cell type: B lymphocyte
    Growth Properties: Suspension, proliferation in clusters
    Description: The RAJI cell line was established in 1963 from blood of a 11 year old male with Burkitt's lymphoma. Although this cells carry the latent Epstein-Barr virus (EBV) genome, the cells are 'non-producers due to deletions within the genome.
    Characterisitics: Cells are positive for EBNA

  • RAJI growing

    Nummer: 330359

    Bestand: 3-5 Tage Lieferzeit
    Human B lymphocyte cell line RAJI

    Organism: Homo sapiens (human)
    Age: 11 year old
    Gender: Male
    Ethnicity: Black
    Tissue: Blood, hematopoietic system
    Disease: Burkitt's lymphoma
    Morphology: Round cells
    Cell type: B lymphocyte
    Growth Properties: Suspension, proliferation in clusters
    Description: The RAJI cell line was established in 1963 from blood of a 11 year old male with Burkitt's lymphoma. Although this cells carry the latent Epstein-Barr virus (EBV) genome, the cells are 'non-producers due to deletions within the genome.
    Characterisitics: Cells are positive for EBNA

  • RJ2.2.5

    Nummer: 300360

    Bestand: Sofort lieferbar
    Biosafety level: L2

    Human B lymphocyte cell line RJ2.2.5
    Sub-clone of RAJI

    Organism: Homo sapiens (human)
    Age: 11 year old
    Gender: Male
    Ethnicity: Black
    Tissue: Blood
    Disease: Burkitt's lymphoma
    Morphology: Lymphoblast-like, round cells
    Cell type: B-LCL, B lymphocyte
    Growth Properties: Suspension, proliferation in clusters
    Description: This HLA-DR negative variant of the RAJI cell line was established in 1983 by R. Accolla.
    Characterisitics: Cells are positive for EBNA


    HLA-Daten:
    Klasse I:
    HLA-A: A*03:01:01
    HLA-B: B*15:10:01
    HLA-C: C*03:04:02,*04:01:01
    HLA-E: E*01:01:01
    Klasse II:
    DRB1: DRB1*03:01:01,*10:01:01
    DQA1: DQA1*01:05:01,*05:01:01
    DQB1: DQB1*02:01:01,*05:01:01
    DPB1: DPB1*01:01:01
  • Ramos

    Nummer: 302007

    Bestand: Sofort lieferbar
    Human B lymphocyte cell line Ramos

    Organism: Homo sapiens (human)
    Age: 3 years old
    Gender: Male
    Ethnicity: Caucasian
    Tissue: Blood, hematopoietic system
    Disease: Burkitt's lymphoma
    Morphology: Lymphoblast-like, round cells
    Cell type: B lymphocyte
    Growth Properties: Suspension, proliferation in clusters
    Description: The Ramos cell line was established in 1972 from blood of a 3 year old male with Burkitt's lymphoma.


    HLA-Daten:
    Klasse I:
    HLA-A: A*03:01:01
    HLA-B: B*44:160Q,*51:01:01
    HLA-C: C*16:01:01
    HLA-E: E*01:03:02
    Klasse II:
    DRB1: DRB1*07:01:01
    DQA1: DQA1*02:01:01
    DQB1: DQB1*02:02:01
    DPB1: DPB1*04:01:01,*104:01:01