Knochen-Tumorzellen



Knochenkrebs ist eine sehr seltene Erkrankung bei Erwachsenen und primäre Knochentumoren sind noch seltener. Die meisten Knochenkrebsarten sind metastasierten Ursprungs und verhalten sich daher wie das Gewebe, aus dem sie stammen.
Osteo- und Chondrosarkome sind die häufigsten primären Knochenkrebse, während Osteo- und Ewing-Sarkome bei Kindern und jungen Erwachsenen am häufigsten auftreten. Jugendliche entwickeln häufiger Knochenkrebs als Erwachsene. Dies könnte auf die Wachstumsschübe während der Pubertät zurückzuführen sein, da sie die Entwicklung von Knochenkrebs begünstigen. Trotz der relativ geringen Inzidenzen von primären Knochenkrebserkrankungen sind die Sterblichkeitsraten, insbesondere bei Kindern und jungen Erwachsenen, überproportional hoch, weshalb die Erforschung dieses Themas von großer Bedeutung ist.


CLS verfügt über eine Sammlung von mehr als zehn bösartigen Knochentumoren der folgenden Typen:

  • Ewing Sarkom

  • Chondrosarkom

  • Osteosarkom


Eine Übersicht über alle derzeitigen Zelllinien isoliert aus Hirntumoren können Sie unter Panel Bone Tumor cell lines als PDF herunterladen.


Artikelübersicht

30 Artikel in dieser Kategorie gefunden

  • CADO-ES1

    Nummer: 300127

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    Human Bone Ewing´s sarcoma cell line CADO-ES1

    Organism: Homo sapiens (human)
    Ethnicity: Japanese
    Age: 19 years
    Gender: Female
    Tissue: Ewing’s sarcoma
    Morphology: Small round tumor cells
    Cell type: Ewing’s sarcoma
    Growth Properties: Monolayer, semi-adherent; the cells form distinct colonies which may proliferate as loosely adherent clusters or spheres.
    Description: Established from the malignant pleural effusion of a 19 years old Japanese. The cells may grow as tumor spheres when cultured under serum-free conditions.


  • CADO-ES1 growing

    Nummer: 330127

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    Human Bone Ewing´s sarcoma cell line CADO-ES1

    Organism: Homo sapiens (human)
    Ethnicity: Japanese
    Age: 19 years
    Gender: Female
    Tissue: Ewing’s sarcoma
    Morphology: Small round tumor cells
    Cell type: Ewing’s sarcoma
    Growth Properties: Monolayer, semi-adherent; the cells form distinct colonies which may proliferate as loosely adherent clusters or spheres.
    Description: Established from the malignant pleural effusion of a 19 years old Japanese. The cells may grow as tumor spheres when cultured under serum-free conditions.

  • HOS (TE85)

    Nummer: 300449

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    Human Bone Osteosarcoma cell line HOS (TE85)

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 13 years
    Gender: Female
    Tissue: Bone
    Morphology: A mixture of fibroblasts and epithelial like cells
    Celltype: Sarcoma, osteogenic
    Growth Properties: Monolayer, adherent
    Description: HOS cells exhibit a flat morphology, low saturation density, low plating efficiency in soft agar and are sensitive to chemical and viral transformation. The cells express alkaline phosphatase under basal conditions (Clover J, 1994).

  • HOS (TE85) growing

    Nummer: 330449

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    Human Bone Osteosarcoma cell line HOS (TE85)

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 13 years
    Gender: Female
    Tissue: Bone
    Morphology: A mixture of fibroblasts and epithelial like cells
    Celltype: Sarcoma, osteogenic
    Growth Properties: Monolayer, adherent
    Description: HOS cells exhibit a flat morphology, low saturation density, low plating efficiency in soft agar and are sensitive to chemical and viral transformation. The cells express alkaline phosphatase under basal conditions (Clover J, 1994).

  • HS-729

    Nummer: 300443

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    Human Bone Rhabdomysarcoma cell line HS-729

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 74 years old
    Gender: Male
    Tissue: Soft Tissue
    Morphology: Fibroblast
    Celltype: Rhabdomyosarcoma
    Growth Properties: Monolayer, adherent

  • HS-729 growing

    Nummer: 330443

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    Human Bone Rhabdomysarcoma cell line HS-729

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 74 years old
    Gender: Male
    Tissue: Soft Tissue
    Morphology: Fibroblast
    Celltype: Rhabdomyosarcoma
    Growth Properties: Monolayer, adherent


  • KHOS-240S

    Nummer: 300433

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    Human Bone Osteosarcoma cell line KHOS-240S

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 13 years
    Gender: Female
    Tissue: Bone
    Morphology: Fibroblast
    Celltype: Osteosarcoma; osteogenic
    Growth Properties: Monolayer, adherent
    Description: The growth properties of KHOS-240S are similar to HOS (TE-85). The KHOS-240S does not represent a rescuable Kirsten murine sarcoma virus genome.

  • KHOS-240S growing

    Nummer: 330433

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    Human Bone Osteosarcoma cell line KHOS-240S

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 13 years
    Gender: Female
    Tissue: Bone
    Morphology: Fibroblast
    Celltype: Osteosarcoma; osteogenic
    Growth Properties: Monolayer, adherent
    Description: The growth properties of KHOS-240S are similar to HOS (TE-85). The KHOS-240S does not represent a rescuable Kirsten murine sarcoma virus genome.


  • KHOS-312H

    Nummer: 300447

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    Human Bone Osteosarcoma cell line KHOS-312H

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 13 years
    Gender: Female
    Tissue: Bone
    Celltype: Sarcoma, osteogenic
    Growth Properties: Monolayer, adherent
    Description: The growth properties of KHOS-312H are similar to HOS (TE-85). The KHOS-312H does not represent a rescuable Kirsten murine sarcoma virus genome.

  • KHOS-312H growing

    Nummer: 330447

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    Human Bone Osteosarcoma cell line KHOS-312H

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 13 years
    Gender: Female
    Tissue: Bone
    Celltype: Sarcoma, osteogenic
    Growth Properties: Monolayer, adherent
    Description: The growth properties of KHOS-312H are similar to HOS (TE-85). The KHOS-312H does not represent a rescuable Kirsten murine sarcoma virus genome.


  • KHOS-NP

    Nummer: 300235

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    Human Bone Osteosarcoma cell line

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 13 years old
    Gender: Female
    Tissue: Bone
    Celltype: Osteosarcoma
    Growth Properties: Monolayer, adherent
    Description: This cell line was derived from the HOS cell line (TE-85) by transformation using Kirsten murine sarcoma virus (Ki-MSV). The cells exhibit a high saturation density, a high plating efficiency in soft agar and produce tumors in nude mice. The cells are useful producing MSV pseudotypes with various ecotropic and xenotropic murine leukemia viruses. Cells carry the Ki-MSV genome but do not produce infectious virus particles or viral antigens.

  • KHOS-NP growing

    Nummer: 330235

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    Human Bone Osteosarcoma cell line

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 13 years old
    Gender: Female
    Tissue: Bone
    Celltype: Osteosarcoma
    Growth Properties: Monolayer, adherent
    Description: This cell line was derived from the HOS cell line (TE-85) by transformation using Kirsten murine sarcoma virus (Ki-MSV). The cells exhibit a high saturation density, a high plating efficiency in soft agar and produce tumors in nude mice. The cells are useful producing MSV pseudotypes with various ecotropic and xenotropic murine leukemia viruses. Cells carry the Ki-MSV genome but do not produce infectious virus particles or viral antigens.