Kolon-Tumorzellen



Nahezu alle Fälle von Darmkrebs gehen auf gutartige Tumoren zurück, die sich auf der Innenwand des Dickdarms gebildet haben, was bedeutet, dass es sich um Adenokarzinome handelt. Die Leber zeigt häufig eine Metastasierung, da Blut aus dem Darm und dem Rektum dorthin transportiert wird, während Lymphknoten häufig ebenfalls metastasiert sind.
Darmkrebs ist die dritthäufigste Krebsart weltweit, mit über neun Millionen an dieser Krankheit leidenden Menschen im Jahr 2017, und stellt die zweithäufigste Todesursache bei Krebs in westlichen Ländern dar.
CLS verfügt über eine Sammlung von mehr als 70 Krebszelllinien, die insgesamt aus Dickdarmgewebe isoliert wurden. Viele unserer Darmkrebszelllinien wurden in enger Zusammenarbeit mit der PD Dr. rer.nat M. Linnebacher von der Universität Rostock etabliert.


Wir bieten Kolon-Tumorzellen der folgenden Typen an:

  • Kolon Adenokarzinom

  • Metastasen von kolorektalen Karzinomen zu verschiedenen Geweben

  • PDX (Patient-Derived Xenografts) von Kolon Adenokarzinomen


Eine Übersicht über alle derzeitigen Kolon-Zelllinien können Sie hier Panel Colon Tumor cell lines CLS als PDF herunterladen.



Artikelübersicht

159 Artikel in dieser Kategorie gefunden

  • HHC6548 T1 M1

    Nummer: 300832

    Bestand: Sofort lieferbar
    Human Colorectal Adenocarcinoma cell line HHC6548 T1 M1

    Depositor: Michael Linnebacher
    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 26 years
    Gender: Male
    Tissue: Colorectal Cancer (CRC), colon ascendens
    Morphology: Epithelial
    Cell type: Adenocarcinoma, UICC IIIc, TNM stage: T3 N2 MX grading G3
    Growth Properties: Adherent 2D
    Description: This is one cell line out of a series of colon carcinoma cell lines established by PD Dr. Michael Linnebacher.



  • HHC6548 T1 M1 growing

    Nummer: 330832

    Bestand: 3-5 Tage Lieferzeit
    Human Colorectal Adenocarcinoma cell line HHC6548 T1 M1

    Depositor: Michael Linnebacher
    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 26 years
    Gender: Male
    Tissue: Colorectal Cancer (CRC), colon ascendens
    Morphology: Epithelial
    Cell type: Adenocarcinoma, UICC IIIc, TNM stage: T3 N2 MX grading G3
    Growth Properties: Adherent 2D
    Description: This is one cell line out of a series of colon carcinoma cell lines established by PD Dr. Michael Linnebacher.



  • Colo-205 growing

    Nummer: 330380

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    Human Colon Adenocarcinoma cell line Colo-205

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 70 years old
    Gender: Male
    Tissue: Colon (metastatic site: ascites)
    Morphology: Epithelial
    Cell type: Colorectal adenocarcinoma; Dukes' type D
    Growth Properties: Cells grow loosely attached and in suspension
    Description: The cells are CSAp negative (CSAp-).The cells are positive for keratin by immunoperoxidase staining. COLO 205 cells express a 36000 Dalton cell surface glycoprotein related to the GA733-2 tumor associated antigen.
    References: Boerries et al. 2015. Global gene expression progiling analysis reveals reduction of stemness after B-RAF inhibition in colorectal cancer cell lines.

    References:
    Boerries et al. 2015; Global gene expression profiling analysis reveals reduction of stemness after B-RAF inhibition in colorectal cancer cell lines

  • COLO-320 DM

    Nummer: 300153

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    Human Colon Adenocarcinoma cell line COLO-320 DM

    Organism: Homo sapiens (human)
    Ethinicity: Caucasian
    Age: 55 years old
    Gender: Female
    Tissue: Colon; Dukes' type C
    Morphology: Rounded and refractile
    Cell type: Colorectal adenocarcinoma
    Growth Properties: Adherent

  • COLO-320 DM growing

    Nummer: 330153

    Bestand: Sofort lieferbar
    Human Colon Adenocarcinoma cell line COLO-320 DM

    Organism: Homo sapiens (human)
    Ethinicity: Caucasian
    Age: 55 years old
    Gender: Female
    Tissue: Colon; Dukes' type C
    Morphology: Rounded and refractile
    Cell type: Colorectal adenocarcinoma
    Growth Properties: Adherent

  • COLO-60H

    Nummer: 300456

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    Human Colon Carcinoma cell line COLO-60H

    Organism: Homo sapiens (human)
    Age: 73 years old
    Gender: Male
    Tissue: Colon (transversum)
    Morphology: Epithelial
    Cell type: Untreated adenocarcinoma
    Description: The cell line Colo-60H was established from a biopsy of a male patient with an untreated adenocarcinoma by CLS in 1998. The cells are HLA-0201 positive.

  • COLO-60H growing

    Nummer: 330456

    Bestand: 3-5 Tage Lieferzeit
    Human Colon Carcinoma cell line COLO-60H

    Organism: Homo sapiens (human)
    Age: 73 years old
    Gender: Male
    Tissue: Colon (transversum)
    Morphology: Epithelial
    Cell type: Untreated adenocarcinoma
    Description: The cell line Colo-60H was established from a biopsy of a male patient with an untreated adenocarcinoma by CLS in 1998. The cells are HLA-0201 positive.

  • COLO-94H

    Nummer: 300161

    Bestand: Sofort lieferbar
    Human Colon Adenocarcinoma cell line COLO-94H

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 70 years old
    Gender: Male
    Tissue: Colon (ascendes)
    Tumor: Colorectal Adenocarcinoma
    Morphology: Epithelial
    Growth Properties: Monolayer, adherent
    Description: Established from the primary Colorectal Adenocarcinoma of a 70 year-old male by CLS Cell Lines Service in 1998.

  • COLO-94H growing

    Nummer: 330161

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    Human Colon Adenocarcinoma cell line COLO-94H

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 70 years old
    Gender: Male
    Tissue: Colon (ascendes)
    Tumor: Colorectal Adenocarcinoma
    Morphology: Epithelial
    Growth Properties: Monolayer, adherent
    Description: Established from the primary Colorectal Adenocarcinoma of a 70 year-old male by CLS Cell Lines Service in 1998.

  • CX-1

    Nummer: 300159

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    Human Colon Adenocarcinoma cell line CX-1

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 44 years old
    Gender: Female
    Tissue: Colon
    Morphology: Epithelial
    Cell type: Colorectal adenocarcinoma
    Growth Properties: Monolayer, adherent
    Description: The cell line CX-1 is a subclone of the HT-29 cell line.

  • CX-1 growing

    Nummer: 330159

    Bestand: Sofort lieferbar
    Human Colon Adenocarcinoma cell line CX-1

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Age: 44 years old
    Gender: Female
    Tissue: Colon
    Morphology: Epithelial
    Cell type: Colorectal adenocarcinoma
    Growth Properties: Monolayer, adherent
    Description: The cell line CX-1 is a subclone of the HT-29 cell line.

  • DLD-1

    Nummer: 300220

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    Human Colon Adenocarcinoma cell line DLD-1

    Organism: Homo sapiens (human)
    Ethnicity: Caucasian
    Gender: Male
    Age: n.a.
    Tissue: Colon
    Morphology: Epithelial
    Celltype: Adenocarcinoma
    Growth Properties: Adherent 2D, monolayer
    Description: The DLD-1 cell line has the same genetic background as the cell lines HCT-8, HRT-18 and HCT-15, which was confirmed by Vermeulen et al. 1998.